Pakistani officials say at least 27 people were killed when two buses collided in the southern province of Punjab.
Police said the accident took place early on October 17 near the city of Rahim Yar Khan, some 600 kilometers south of the provincial capital, Lahore.
More than 30 people were also injured in the crash.
Rescuers were attempting to pull people out of the wreckage, with fears that the death toll could rise, local government official Zafar Iqbal said.
Prime Minister Nawaz Sharif's office said he has "expressed deep grief and sorrow over the loss of precious lives.”
Poor roads, reckless driving, and badly maintained vehicles kill up to 5,000 people in Pakistan every year, according to government statistics.